The fresh good black line presents the newest You-shaped matchmaking involving the continued x and you may journal cousin possibility
Schematic diagram of the optimal equal-HR method. The red dashed line is parallel to the x-axis, which means Pstep one and Pdos have equal log relative hazard values. The optimal equal-HR method searches pairs of cut-points with equal log relative hazard values as candidate cut-points, such as (P1, P2)
The rest of so it report are prepared as follows. The important points of one’s optimal equivalent-Hour approach are showed into the 2nd Part ‘Methods’. The fresh performance of your maximum equivalent-Hr method is in contrast to most other popular discretization tips regarding discrimination energy and you can results via a simulation study. We expose this new simulator setup into the Area ‘The newest Simulation Study’. The outcome of your simulation study and the applying of new max equal-Hour approach into a bona fide dataset from brief phone cancer of the lung was displayed when you look at the Point ‘Results’. In the end, you’ll find dialogue and you can results.
Methods
where h(t) denotes the hazard function, h0(t) denotes the baseline hazard function, t is the observed survival times, X is a vector of covariates, and ? (mehr …)